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Pharmacological evaluation of benzotriazole derivatives structurally related to trazodone

✍ Scribed by Perissutti, E.; Meli, R.; Maggetti, S.; Caliendo, G.; Cappello, B.; Silipo, C.; Vittoria, A.; Di Carlo, R.

Book ID
122913209
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
73 KB
Volume
26
Category
Article
ISSN
1043-6618

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Synthesis and biological activity of 1-, 2- or 3-Substituted benzothieno-[2,3-d]triazole derivatives structurally related to trazodone
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## Abstract A series of new 1‐, 2‐ and 3‐piperazinylbenzothieno[2,3‐__d__]triazole derivatives structurally related to Trazodone were prepared and tested for their antiserotonergic, antiadrenergic and antihistaminergic __in vitro__ activities together with their analgesic __in vivo__ activity by us