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Synthesis and biological activity of benzotriazole derivatives structurally related to trazodone

✍ Scribed by G Caliendo; R Di Carlo; G Greco; R Meli; E Novellino; E Perissutti; V Santagada


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
713 KB
Volume
30
Category
Article
ISSN
0223-5234

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Synthesis and biological activity of 1-,
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## Abstract A series of new 1‐, 2‐ and 3‐piperazinylbenzothieno[2,3‐__d__]triazole derivatives structurally related to Trazodone were prepared and tested for their antiserotonergic, antiadrenergic and antihistaminergic __in vitro__ activities together with their analgesic __in vivo__ activity by us