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Pharmacokinetics:Pharmacokinetic Differences Between Lansoprazole Enantiomers in Rats

โœ Scribed by KAZUHIKO ARIMORI; KAZUTO YASUDA; HISAKAZU KATSUKI; MASAHIRO NAKANO


Book ID
118111135
Publisher
Pharmaceutical Press
Year
1998
Tongue
English
Weight
474 KB
Volume
50
Category
Article
ISSN
2042-7158

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5-Dimethylsulfamoyl-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxyli c acid (DBCA), a promising uricosuric, diuretic, and antihypertensive agent, was administered intravenously to rats. The levels of DBCA in plasma and the areas under the curve of concentration versus time (AUC values) of the S(-)-ena