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Pharmacokinetic Differences between Pantoprazole Enantiomers in Rats

โœ Scribed by Zhiyong Xie; Yini Zhang; Haiyan Xu; Dafang Zhong

Book ID
106492652
Publisher
Springer US
Year
2005
Tongue
English
Weight
338 KB
Volume
22
Category
Article
ISSN
0724-8741

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5-Dimethylsulfamoyl-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxyli c acid (DBCA), a promising uricosuric, diuretic, and antihypertensive agent, was administered intravenously to rats. The levels of DBCA in plasma and the areas under the curve of concentration versus time (AUC values) of the S(-)-ena