Pharmacokinetic parameters of two antifolates, trimethoprim and aditoprim, were studied in buffalo calves. The elimination half-life of aditoprim (6-14 h) was nearly twice as long as that of trimethoprim (3.08h) and compares well with values observed in heifers. This longer half-life of aditoprim is
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Pharmacokinetics of trimethoprim in the rat
โ Scribed by Yu-Hsing Tu; Loyd V. Allen Jr.; Vincent M. Fiorica; Donald D. Albers
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 529 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0022-3549
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