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Pharmacokinetics of the thymidine analog 2′-fluoro-5-methyl-1-β-d-arabinofuranosyluracil (FMAU) in tumor-bearing rats

✍ Scribed by James R. Bading; Antranik H. Shahinian; Amy Vail; Pravin Bathija; G.W. Koszalka; Robert T. Koda; Mian M. Alauddin; John D. Fissekis; Peter S. Conti

Book ID
116798755
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
309 KB
Volume
31
Category
Article
ISSN
0969-8051

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Synthesis of [18F]-labeled 2′-deoxy-2′-fluoro-5-methyl-1-β-D-arabinofuranosyluracil ([18F]-FMAU)
✍ Mian M. Alauddin; Peter S. Conti; John D. Fissekis 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 100 KB 👁 1 views

## Abstract Synthesis of 2′‐deoxy‐2′‐[^18^F]fluoro‐5‐methyl‐1‐__β__‐D‐arabinofuranosyluracil ([^18^F]‐FMAU) is reported. 2‐Deoxy‐2‐[^18^F]fluoro‐1,3,5‐tri‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** was prepared by the reaction of the respective triflate **1** with tetrabutylammonium[^18^F]fluoride. Th