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Pharmacokinetics of sotalol during pregnancy

✍ Scribed by M. F. O'Hare; W. Leahey; G. A. Murnaghan; D. G. McDevitt

Publisher
Springer
Year
1983
Tongue
English
Weight
454 KB
Volume
24
Category
Article
ISSN
0031-6970

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The pharmacokinetics of d-sotalol has been studied in six healthy volunteers given single doses of 0.25, 0.50, 1, 2 mg.kg-1 i.v. and one 100 mg oral dose in comparison with the kinetics of 1 mg.kg-1 i.v. of dl-sotalol. There was no significant difference in the disposition of the d-enantiomer and th