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Pharmacokinetics of prednisolone in children with acute lymphoblastic leukaemia

✍ Scribed by Imtiaz Choonara; John Wheeldon; Phil Rayner; Mike Blackburn; Ian Lewis

Publisher
Springer
Year
1989
Tongue
English
Weight
285 KB
Volume
23
Category
Article
ISSN
0344-5704

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Intraindividual variation in 6-mercaptop
Intraindividual variation in 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute lymphoblastic leukaemia
✍ P. Lafolie; S. Hayder; O. BjΓΆrk; C. Peterson πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 318 KB

Intraindividual variation in 6-mercaptopurine (6-MP) kinetics has been little studied. It has now been examined in 18 children with acute lymphoblastic leukaemia (ALL). On 2 to 4 occasions in each patient drug concentrations in plasma and red cells were followed for 4 h after administration by means