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Pharmacokinetics of intravenous and oral DA-8159, a new erectogenic, in rats with protein-calorie malnutrition

✍ Scribed by Hyun J. Shim; Yu C. Kim; Joo H. Lee; Byung O. Ahn; Jong W. Kwon; Won B. Kim; Inchul Lee; Myung G. Lee


Book ID
111769445
Publisher
Pharmaceutical Press
Year
2004
Tongue
English
Weight
163 KB
Volume
56
Category
Article
ISSN
2042-7158

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## Abstract The changes in pharmacokinetics of DA‐8159 by omeprazole with respect to inhibition of CYP3A1/2 in rats were evaluated. After oral administration of DA‐8159 at dose of 30 mg/kg to rats pretreated with oral omeprazole at 30 mg/kg for 1 week, the total area under the plasma concentration–