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Pharmacokinetics of Buspirone following Oral Administration to Rhesus Monkeys

โœ Scribed by PUNIT H. MARATHE; FRANK SHEN; PETER MARKHAM; DOUGLAS S. GREENE

Book ID
111769791
Publisher
Pharmaceutical Press
Year
1999
Tongue
English
Weight
111 KB
Volume
51
Category
Article
ISSN
2042-7158

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โœ Jack A. Cook; Paula J. Burger; Barbara M. Michniewicz; Gerald D. Nordblom; Gary ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 163 KB ๐Ÿ‘ 1 views

The purpose of this study was to characterize CI-992 pharmacokinetics and pharmacokinetics/pharmacodynamics (PK/PD) in sodium deplete monkeys. Panels of monkeys were administered CI-992 as a 1 h intravenous infusions (0.1 and 1 mg kg -1 ) or as single oral doses (0, 10, 50, and 100 mg kg -1 ). Mean