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Pharmacokinetics of carbamazepine in monkeys following intravenous and oral administration

โœ Scribed by R. H. Levy; J. S. Lockard; J. R. Green; P. Friel; L. Martis

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
561 KB
Volume
64
Category
Article
ISSN
0022-3549

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The purpose of this study was to characterize CI-992 pharmacokinetics and pharmacokinetics/pharmacodynamics (PK/PD) in sodium deplete monkeys. Panels of monkeys were administered CI-992 as a 1 h intravenous infusions (0.1 and 1 mg kg -1 ) or as single oral doses (0, 10, 50, and 100 mg kg -1 ). Mean