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Pharmacokinetics of aniracetam and its metabolites in rats

✍ Scribed by Taro Ogiso; Masahiro Iwaki; Tadatoshi Tanino; Kazuyuki Ikeda; Tsuyoshi Paku; Yoshihide Horibe; Hiroko Suzuki

Book ID
109388952
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
71 KB
Volume
87
Category
Article
ISSN
0022-3549

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Stobadin dihydrochloride was administered p.0. to rats at a dose of lmg kg-' once daily for 25 consecutive days. The peak and trough concentrations of the sum of stobadin metabolites, determined from Days 6 1 6 of treatment, demonstrated a steady-state. The mean daily excretion of 'H-radioactivity d