Pharmacokinetics of an HIV-1 gp120-specific chimeric antibody in patients with HIV-1 disease
✍ Scribed by J. Schüpbach; H. Günthard; M. S. C. Fung; R. -S. Liou; L. Botta; P. Gowland; W. Gordon; D. Gygax; N. T. Chang; T. W. Chang; R. Lüthy; D. G. Braun
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 857 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0921-299X
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## Abstract ## Background Previously we reported that human CD4^+^ T cell lines stably expressing anti‐HIV‐1 gag p17 scFv/Cκ in the cytosol or nucleus were resistant to HIV‐1 challenge. Inhibition of HIV‐1 by anti‐HIV‐1 gag p17 scFv/Cκ occurred at both the pre‐ and post‐integration steps of the vi