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Pharmacokinetics, bioavailability and absorption of flumequine in the rat

✍ Scribed by Ana Ruiz-Garcı́a; Marival Bermejo; Virginia Merino; Gloria Sánchez-Castaño; Joan Freixas; Teresa Ma Garrigues

Book ID
117640109
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
107 KB
Volume
48
Category
Article
ISSN
0939-6411

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In a pharmacokinetic study, 15, 30, 60, and 150 mg kg-' intravenous and oral doses of methocarbamol were administered to rats. Differences observed in plasma clearance values, i.e. 0~0203,0~0156,0~0123, and 0-0085 1 kg-' min-' for 15,30,60, and 150 mg kg-', respectively, suggested a dosedependent ph