Zaleplon pharmacokinetics and absolute b
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Amy S. Rosen; Philippe FourniΓ©; Mona Darwish; Philippe Danjou; Steven M. Troy
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Article
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1999
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John Wiley and Sons
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English
β 115 KB
The pharmacokinetics and absolute oral bioavailability of zaleplon were assessed to evaluate the extent of presystemic metabolism of this new nonbenzodiazepine hypnotic agent. A partially randomized, single-dose, four-period crossover study was conducted in 23 healthy subjects. Subjects received 1 a