Absolute bioavailability and pharmacokinetics of medifoxamine in healthy humans.
β Scribed by S Saleh; A Johnston; P Turner
- Book ID
- 117945040
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 447 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0306-5251
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π SIMILAR VOLUMES
Medifoxamine is a monoamine reuptake inhibiting antidepressant drug. We have investigated its pharmacokinetics in normal healthy volunteers. After an overnight fast, ascending doses of 200, 500, 750 and 1000 mg of medifoxamine were taken orally. Plasma samples were analysed using a specific HPLC met
The objective of the current investigation was to describe the pharmacokinetics and absolute oral bioavailability of epristeride. Twelve healthy male subjects (mean (SD) age, 27 (6.2) years) received a single oral dose of 5mg and an intravenous infusion of 4.5 mg over 30 min in a crossover fashion.