Pharmacokinetics and toxicity of high-dose intravenous methotrexate in the treatment of leptomeningeal carcinomatosis
β Scribed by Merry L. Tetef; Kim A. Margolin; James H. Doroshow; Steven Akman; Lucille A. Leong; Robert J. Morgan Jr.; James W. Raschko; Neil Slatkin; George Somlo; Jeffrey A. Longmate; Mary I. Carroll; Edward M. Newman
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 121 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0344-5704
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## Abstract ## Background. Nasopharyngeal carcinoma with leptomeningeal involvement is rare and typically has poor prognosis. ## Methods and Results. We present a case report of a patient with nasopharyngeal carcinoma who was treated with highβdose intravenous methotrexate and remains asymptomat
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