There are few pharmacokinetic data for mycophenolate mofetil (MMF) when used in combination with cyclosporine (CsA) in pediatric liver transplant recipients. The aim of this study was to assess the pharmacokinetics of MMF in stable pediatric liver transplant patients and estimate the dose of MMF req
Pharmacokinetics and pharmacodynamics of mycophenolic acid in stable renal transplant recipients treated with low doses of mycophenolate mofetil
✍ Scribed by M. Brunet; J. Martorell; F. Oppenheimer; J. Vilardell; O. Millán; M. Carrillo; I. Rojo; J. Corbella
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 98 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0934-0874
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📜 SIMILAR VOLUMES
The bioavailability of mycophenolic acid (MPA) after oral administration of mycophenolate mofetil (MMF) has been reported to be more than 90% in healthy volunteers, and in kidney and thoracic organ transplant patients. Such information is limited in liver transplant (LTx) patients. The present study
The pharmacokinetics of mycophenolate mofetil (MMF) in liver transplant recipients may change because of pharmacokinetic interactions with coadministered immunosuppressants or because changes in the enterohepatic anatomy may affect biotransformation of MMF to mycophenolic acid (MPA) and enterohepati