Pharmacokinetics and tolerance of mycophenolate mofetil in renal transplant children
โ Scribed by E. Jacqz-Aigrain; E. Khan Shaghaghi; V. Baudouin; M. Popon; D. Zhang; A. Maisin; C. Loirat
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 56 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0931-041X
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๐ SIMILAR VOLUMES
There are few pharmacokinetic data for mycophenolate mofetil (MMF) when used in combination with cyclosporine (CsA) in pediatric liver transplant recipients. The aim of this study was to assess the pharmacokinetics of MMF in stable pediatric liver transplant patients and estimate the dose of MMF req
Mycophenolate mofetil (MM) is the ester derivative of mycophenolic acid (MPA), which exerts immunosuppressive activity by inhibiting de novo purine biosynthesis. Following animal models and pilot studies in human renal allograft recipients that confirmed MM's ability to prevent and half rejection ep
The bioavailability of mycophenolic acid (MPA) after oral administration of mycophenolate mofetil (MMF) has been reported to be more than 90% in healthy volunteers, and in kidney and thoracic organ transplant patients. Such information is limited in liver transplant (LTx) patients. The present study