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Pharmacokinetics and pharmacodynamics of locoregional 5 fluorouracil (5FU) in advanced colorectal liver metastases

✍ Scribed by Goldberg, JA; Kerr, DJ; Willmott, N; McKillop, JH; McArdle, CS


Book ID
109836060
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
663 KB
Volume
57
Category
Article
ISSN
0007-0920

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Intraperitoneal 5-fluorouracil (5-FU) was given to eight patients with unresectable colorectal liver cancer and to one patient after radical hepatectomy . A subcutaneous intraperitoneal access device was implanted, and treatment consisted of continuous infusion of 1,OOO mg 5-FU/d for 5 days, repeate