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746 - Oxaliplatin (LOHP) and 5-fluorouracil (5-FU) synergism in advanced colorectal cancer patients (ACRC)

✍ Scribed by V. Meyer; R. Delva; E. Gamelin; B. Lamezec; P. Maillart; E. Danquechin-Dorval; A. Lortholary; M. Boisdron-Celle; M. Maigre; S. Brienza; E. Cvitkovic; F. Larra

Book ID: 117664992
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 261 KB
Volume: 33
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(97)85368-3

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738 - Addition of oxaliplatin (Eloxatine

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## BACKGROUND. A phase I1 prospective trial was carried out to study the concept of 5-fluorouracil (5-FU) dose-intensity in patients with advanced colorectal cancer. Forty patients were treated with 5-FU plus leucovorin (LV), with individually increasing doses of 5-FU. A 5-FU pharmacokinetic follo