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760 Methotrexate (MTX) and 5-fluorouracil (5-FU) in advanced colorectal cancer patients previously treated with adjuvant 5-FU

โœ Scribed by P. Pronzato; F. Vaira; A. Viganni; P. Losardo; G. Bertelli


Book ID
116167506
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
122 KB
Volume
31
Category
Article
ISSN
0959-8049

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Relationship between 5-fluorouracil (5-F
โœ Erick C. Gamelin; Etienne M. Danquechin-Dorval; Yvan F. Dumesnil; Philippe J. Ma ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 977 KB

## BACKGROUND. A phase I1 prospective trial was carried out to study the concept of 5-fluorouracil (5-FU) dose-intensity in patients with advanced colorectal cancer. Forty patients were treated with 5-FU plus leucovorin (LV), with individually increasing doses of 5-FU. A 5-FU pharmacokinetic follo