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Sequential methotrexate(MTX) and 5-fluorouracil(FU) in metastatic colorectal cancer(CRC). Results of a phase II study

✍ Scribed by Thimmappaya, Bayar; Weissman, Sherman M.

Book ID
121962088
Publisher
Elsevier Science
Year
1986
Weight
132 KB
Volume
22
Category
Article
ISSN
0277-5379

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A phase II study of sequential methotrex
A phase II study of sequential methotrexate and fluorouracil in advanced colorectal cancer
✍ L. Panasci; J. Ford; R. Margolese πŸ“‚ Article πŸ“… 1985 πŸ› Springer 🌐 English βš– 242 KB

Twenty-nine patients with advanced colorectal cancer were treated with methotrexate (MTX) 200 mg/m2 followed 1 h later by fluorouracil (FU) (1000 mg/m2) and 24 h later by oral leucovorin 20 mg every 6 h for six doses. The cycle was repeated every 2 weeks. Among the 25 evaluable patients there were 2