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Pharmacokinetics and Anticonvulsant Activity of Three Monoesteric Prodrugs of Valproic Acid

✍ Scribed by Khalil Badir; Abdulla Haj-Yehia; Tom B. Vree; Eppo Kleijn; Meir Bialer


Book ID
110341873
Publisher
Springer US
Year
1991
Tongue
English
Weight
686 KB
Volume
08
Category
Article
ISSN
0724-8741

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Pharmacokinetic analysis and anticonvuls
✍ Salim Hadad; Tom B. Vree; Eppo Van Der Kleijn; Meir Bialer πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 464 KB πŸ‘ 2 views

## Abstract The pharmacokinetics of the following two polyesteric prodrugs of valproic acid (VPA) have been investigated: 1,4‐butanediol divaiproate (BDV) and glyceryl trivalproate (GTV). In addition, the anticonvulsant activity of these compounds has been evaluated and compared to that of VPA and