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Synthesis and Anticonvulsant Activity of N-Benzyloxycarbonyl-Amino Acid Prodrugs of Phenytoin

✍ Scribed by GERHARD K. E. SCRIBA; DIDIER M. LAMBERT

Book ID
111769803
Publisher
Pharmaceutical Press
Year
1999
Tongue
English
Weight
72 KB
Volume
51
Category
Article
ISSN
2042-7158

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Synthesis and anticonvulsant activity of
Synthesis and anticonvulsant activity of N,N-phthaloyl derivatives of central nervous system inhibitory amino acids
✍ Cyril O. Usifoh; Didier M. Lambert; Johan Wouters; Gerhard K. E. Scriba πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 124 KB πŸ‘ 2 views

In order to study the influence of the length of the amino acid chain of N,N-phthaloyl-amino acid amides as analogues of the former anticonvulsant taltrimide on the seizure-antagonizing activity glycine, beta-alanine and gamma-aminobutyric acid (GABA) derivatives were synthesized. The corresponding