Pharmacokinetic properties and metabolism of idebenone
✍ Scribed by Klaus Kutz; Jürgen Drewe; Pierre Vankan
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 227 KB
- Volume
- 256
- Category
- Article
- ISSN
- 0340-5354
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📜 SIMILAR VOLUMES
The metabolism of encainide occurs in the liver and is polymorphically distributed according to the same genetic factor that determines the 4-hydroxylation of debrisoquine. Over 90% of patients are extensive metabolizers (EM) in whom the oral bioavailability of encainide is only 30% because of exten
Codeine (30 mg phosphate) was metabolized by eight human volunteers to the following six metabolites: codeine-6-glucuronide 81 .O+ 9.3 per cent, norcodeine 2.16? 1.44 per cent, morphine 0-562 0-39 per cent, morphine-3-glucuronide 2-10? 1-24 per cent, morphine-6-glucuronide 0-80k 0.63 per cent, and n