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Pharmacokinetic-Pharmacodynamic Relationships of Apomorphine in Patients with Parkinson’s Disease

✍ Scribed by Dr Cees Neef, Teus van Laar

Book ID
119926250
Publisher
Springer International Publishing AG
Year
1999
Tongue
English
Weight
204 KB
Volume
37
Category
Article
ISSN
0312-5963

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## Abstract We explored the potential effect of catechol‐__O__‐methyltransferase (COMT) genetic polymorphism on the pharmacokinetics and pharmacodynamics of a standard oral dose of levodopa in patients with Parkinson's disease (PD). We prospectively collected blood samples for COMT genotyping from