Pharmacokinetic interaction of contraceptive steroids with prednisone and prednisolone
โ Scribed by B. M. Frey; H. J. Schaad; F. J. Frey
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 764 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Three simple linear and three simple non-linear pharmacokinetic models are presented which incorporate the reversible metabolism that occurs between prednisone and prednisolone. Under steady-state conditions it is possible to not only distinguish between the linear and non-linear models but also to
The protein binding characteristics of prednisone and prednisolone were determined in human and rabbit plasma and in a 4.7 per cent human serum albumin (HSA) solution. The influence of plednisolone on prednisone binding in human plasma was also examined. Prednisolone exhibited nonlinear binding and