A rabbit model for investigating sublingual drug absorption was established yielding results consistent with clinical data reported in the literature. Using propranolol as a model compound the effect of formulation and dosing variables was explored as a means to characterize the limiting parameters
Pharmacokinetic data of propranolol enantiomers in a comparative human study with (S)- and (R,S)-propranolol
β Scribed by W. Lindner; M. Rath; K. Stoschitzky; H. J. Semmelrock
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 404 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0899-0042
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The effect of Abana and propranolol on left ventricular hypertrophy in hypertensive individuals was studied by echocardiography. The study showed an improvement in cardiac function as indicated by an increase in ejection fraction and fractional shortening in both the Abana-and propranolol-treated gr
A nocturnal increase in portal pressure and blood flow was demonstrated in patients with cirrhosis, suggesting Patients. Fourteen patients with cirrhosis (10 men and 4 women, that these hemodynamic changes may contribute to the mean age 53 { 6 years [mean { SEM]; range, 35-63 years) were triggering