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A rabbit model for sublingual drug delivery: Comparison with human pharmacokinetic studies of propranolol, verapamil and captopril

โœ Scribed by Dali, Manisha M. (author);Moench, Paul A. (author);Mathias, Neil R. (author);Stetsko, Paul I. (author);Heran, Christopher L. (author);Smith, Ronald L. (author)


Publisher
John Wiley and Sons Inc.
Year
2006
Tongue
English
Weight
109 KB
Volume
95
Category
Article
ISSN
0022-3549

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A rabbit model for sublingual drug deliv
โœ Dali, Manisha M. (author);Moench, Paul A. (author);Mathias, Neil R. (author);Ste ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 109 KB

A rabbit model for investigating sublingual drug absorption was established yielding results consistent with clinical data reported in the literature. Using propranolol as a model compound the effect of formulation and dosing variables was explored as a means to characterize the limiting parameters