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Pharmacokinetic and Pharmacodynamic Modeling of Recombinant Human Erythropoietin after Intravenous and Subcutaneous Dose Administration in Cynomolgus Monkeys

✍ Scribed by Ramakrishnan, R.


Book ID
126663117
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2003
Tongue
English
Weight
216 KB
Volume
306
Category
Article
ISSN
0022-3565

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The pharmacokinetics of recombinant human Epo (rHuEpo) were investigated after subcutaneous administration to horses. Four horses received a single 30 IU kg-' dose of rHuEpo. One horse received three repeated doses of 120 IU kg-' at 48 h intervals. Plasma erythropoietin (Epo) was measured by radioim