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Pharmacokinetic and Pharmacological Profiles of Free and Liposomal Recombinant Human Erythropoietin After Intravenous and Subcutaneous Administrations in Rats

โœ Scribed by Hidetaka Moriya; Yoshie Maitani; Naoto Shimoda; Kozo Takayama; Tsuneji Nagai


Book ID
110309203
Publisher
Springer US
Year
1997
Tongue
English
Weight
565 KB
Volume
14
Category
Article
ISSN
0724-8741

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โœ Agnes Souillard; Michel Audran; Francoise Bressolle; Philippe Jaussaud; Raynald ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 568 KB

The pharmacokinetics of recombinant human Epo (rHuEpo) were investigated after subcutaneous administration to horses. Four horses received a single 30 IU kg-' dose of rHuEpo. One horse received three repeated doses of 120 IU kg-' at 48 h intervals. Plasma erythropoietin (Epo) was measured by radioim