## Abstract Twenty children 1β17 (median, 5.5) years of age received GMβCSF during chemotherapyβinduced neutropenia at the dose of 5 ΞΌg/kg/day, continued until the absolute neutrophil count (ANC) exceeded 500 Γ 10^6^/liter. Twelve children with solid tumors received GMβCSF after courses of conventi
Pharmacokinetics of recombinant human granulocyte-macrophage colony-stimulating factor in children after intravenous and subcutaneous administration
β Scribed by Norbert Stute; William E. Evans; Wayne I. Furman; Michael Schell
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 703 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0022-3549
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Combinations of low dosages of purified recombinant human (rh) macrophagecolony stimulating factor (M-CSF; also termed CSF-1) and rh granulocyte-colony stimulating factor (G-CSF) were compared alone and in combination for their influence on the cycling rates and numbers of bone marrow and splenic gr
is a fellow of Ministerio de Educaci6n y Ciencia. J. Bartolome and J.A. Quiroga are recipients of research grants from Fundacion para el Estudio de las Hepatitis Vudes.
Fourteen patients with Hodgkin's disease (two previously untreated, 12 following relapse or with refractory disease) were treated with a combination chemotherapy regimen comprising chlorambucil, vinblastine, procarbazine, prednisolone, etoposide, vincristine and adriamycin administered on days 1-8.