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Pharmacokinetic Analysis and Antiepileptic Activity of Tetra-Methylcyclopropane Analogues of Valpromide

✍ Scribed by Meir Bialer; Salim Hadad; Bashier Kadry; Ali Abdul-Hai; Abdulla Haj-Yehia; Jeff Sterling; Yaacov Herzig; Boris Yagen


Book ID
110344789
Publisher
Springer US
Year
1996
Tongue
English
Weight
918 KB
Volume
13
Category
Article
ISSN
0724-8741

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Pharmacokinetic analysis and antiepilept
✍ Salim Hadad; Meir Bialer πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 151 KB πŸ‘ 2 views

Valproyl glycinamide (TV 1901-VPGD) is a new antiepileptic drug, which is currently undergoing clinical trials. The present study explored the pharmacokinetics and pharmacodynamics (anticonvulsant activity and neurotoxicity) of two new isomers of valproyl glycinamide: valnoctyl glycinamide (VCGD) an