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Structure–Pharmacokinetic Relationships in a Series of Valpromide Derivatives with Antiepileptic Activity

✍ Scribed by Abdulla Haj-Yehia; Meir Bialer


Book ID
114421050
Publisher
Springer US
Year
1989
Tongue
English
Weight
1022 KB
Volume
06
Category
Article
ISSN
0724-8741

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Structure–pharmacokinetic relationships
✍ Abdulla Haj-Yehia; Meir Bialer 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 637 KB

Valpromide (VPD) and valnoctamide (VCD) are two isomers which are aliphatic amides derived from short fatty acids that possess anticonvulsant activity. Our previous studies with VPD, VCD, and other related compounds showed that the biotransformation of these amides to their respective homologous ac