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Pharmaceutical development of a parenteral lyophilized formulation of the investigational antitumor neuropeptide antagonist [Arg6, D-Trp7,9, MePhe8]-Substance P {6-11}

โœ Scribed by J.D. Jonkman-de Vries; H. Rosing; H. Talsma; R.E.C. Henrar; J.J. Kettenes-van den Bosch; A. Bult; J.H. Beijnen


Book ID
110231562
Publisher
Springer US
Year
1998
Tongue
English
Weight
113 KB
Volume
16
Category
Article
ISSN
0167-6997

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๐Ÿ“œ SIMILAR VOLUMES


Degradation Kinetics of Antagonist [Arg6
โœ J.L.E. Reubsaet; J.H. Beijnen; A. Bult; O.A.G.J. Vanderhouwen; J. Teeuwsen; E.H. ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 576 KB

Antagonist \(\left[\mathrm{Arg}^{6}\right.\), D-Trp \({ }^{7,9}\), MePhe \(\left.^{8}\right]\)-substance P \{611) was subjected to a systematic stability study in which kinetic parameters were obtained for the degradation of this hexapeptide under several well-defined conditions. The influences of \

Reversed-Phase High-Performance Liquid C
โœ J.L.E. Reubsaet; J.H. Beijnen; A. Bult; J. Teeuwsen; E.H.M. Koster; J.C.M. Water ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 409 KB

Reversed-phase high-performance liquid chromatography and capillary zone electrophoresis are widely used in protein and peptide analysis. Degradation of the basic peptide \(\left[\right.\) Arg \(^{6}\), D-Trp \({ }^{7,9}\), MePhe \(\left.^{8}\right]\)-substance P \(\{6-\) 11 (antagonist G) was monit