𝔖 Bobbio Scriptorium
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Phage display: protein engineering by directed evolution

✍ Scribed by Karyn T O'Neil; Ronald H Hoess

Book ID
116165995
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
907 KB
Volume
5
Category
Article
ISSN
0959-440X

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Peptides derived from almost all proteins, including disease-associated proteins, can be presented on the cell surface as peptide-human leukocyte antigen (pHLA) complexes. T cells specifically recognize pHLA with their clonally rearranged T-cell receptors (TCRs), whose natural affinities are limited