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PF1022A: A new potential antifilarial agent

✍ Scribed by Fujimaki, Y; Mori, Y; Terada, M; Aoki, Y


Book ID
123055910
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
149 KB
Volume
47
Category
Article
ISSN
1383-5769

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For receptor binding studies and the elucidation of the mode of action of the potent anthelmintic compound PF1022A a tritium labeled compound with very high specific activity was necessary. Tritium was introduced into the compound by methylation of the [bis-N-demethyl]precursor of PF1022A (PFlO22-2