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Persistent, Low-Dose 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure: Effect on Aryl Hydrocarbon Receptor Expression in a Dioxin-Resistance Model

✍ Scribed by Monique-Andrée Franc; Raimo Pohjanvirta; Jouko Tuomisto; Allan B. Okey


Book ID
112268398
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
219 KB
Volume
175
Category
Article
ISSN
0041-008X

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## Abstract Epidemiological and laboratory studies suggested that exposure to 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) affects glucose homeostasis and increases the incidence of type 2 diabetes mellitus. To evaluate the effects of TCDD on insulin secretion from islets of Langerhans (islets),