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Effect of chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin in female rats on ovarian gene expression

✍ Scribed by Kelli E. Valdez; Zhanquan Shi; Alison Y. Ting; Brian K. Petroff


Book ID
113875496
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
371 KB
Volume
28
Category
Article
ISSN
0890-6238

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## Abstract Epidemiological and laboratory studies suggested that exposure to 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) affects glucose homeostasis and increases the incidence of type 2 diabetes mellitus. To evaluate the effects of TCDD on insulin secretion from islets of Langerhans (islets),