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Peroxynitrite-modified DNA: a better antigen for systemic lupus erythematosus anti-DNA autoantibodies

✍ Scribed by Safia Habib; Moinuddin; Rashid Ali


Book ID
111718091
Publisher
Portland Press
Year
2006
Tongue
English
Weight
241 KB
Volume
43
Category
Article
ISSN
0885-4513

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Limited Anti-DNA Antibody Specificity in
✍ Ronald N. Berzofsky; Carole A. Dorsch; Mary Betty Stevens πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 English βš– 477 KB πŸ‘ 2 views

## Abstract Twenty‐one sera from 11 patients with systemic lupus erythematosus were titrated with ^125^I‐ss‐calf thymus DNA to determine their maximum capacity to bind DNA. Only five sera were capable of binding > 90% of the input DNA. The remaining sixteen sera showed maximum DNA binding levels be