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Peroxisome Proliferator-Activated Receptor Agonists Inhibit Inflammatory Edema and Hyperalgesia

✍ Scribed by Bradley K. Taylor; Niren Dadia; Carolyn B. Yang; Sendhil Krishnan; Mostafa Badr


Book ID
110337346
Publisher
Springer
Year
2002
Tongue
English
Weight
158 KB
Volume
26
Category
Article
ISSN
0360-3997

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## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE