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Peroxisome proliferator–activated receptor γ agonists: Potential use for treating chronic inflammatory diseases

✍ Scribed by James C. Oates; Christopher M. Reilly; Michelle B. Crosby; Gary S. Gilkeson


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
221 KB
Volume
46
Category
Article
ISSN
0004-3591

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## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE