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Penetration of tinidazole into skin blister fluid following its oral administration

✍ Scribed by A. Klimowicz; A. Nowak; S. Bielecka-Grzela


Publisher
Springer
Year
1992
Tongue
English
Weight
536 KB
Volume
43
Category
Article
ISSN
0031-6970

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Two-stage penetration of a single oral d
✍ A. Nowak; A. Klimowicz πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 411 KB

The time-dependent concentration curves of sulphadimethoxine in plasma and cantharidin-induced skin blister fluid have been evaluated following a single oral dose of 1 g. In contrast to other drugs, sulphadimethoxine exhibited two-stage penetration into the blister fluid, the second peak concentrati