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Pd/C-catalyzed, copper-free Sonogashira coupling: one-pot synthesis of 1-aryl-4-(2-phenylethynyl)[1,2,4]triazolo[4,3-a]quinoxalines in water

โœ Scribed by Mohammad Bakherad, Saeideh Jajarmi


Book ID
120919759
Publisher
Springer Vienna
Year
2013
Tongue
English
Weight
371 KB
Volume
144
Category
Article
ISSN
0026-9247

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An efficient synthesis of 2-benzylimidazo[1,2-a]pyrimidines in water is accomplished via Pd/C-catalyzed reaction of 2-imino-1-(2-propynyl)pyrimidine with various aryl iodides in the presence of K 2 CO 3 as the base.