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Copper(II) chloride mediated synthesis and DNA photocleavage activity of 1-aryl/heteroaryl-4-substituted-1,2,4-triazolo[4,3-a]quinoxalines

✍ Scribed by Ranjana Aggarwal; Garima Sumran; Virender Kumar; Ashwani Mittal

Book ID: 113583183
Publisher: Elsevier Science
Year: 2011
Tongue: French
Weight: 595 KB
Volume: 46
Category: Article
ISSN: 0223-5234
DOI: 10.1016/j.ejmech.2011.10.032

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## Abstract Some 1,2,4‐triazolo[4,3‐__a__]quinoxalines 1–10, and 1,2,4‐triazino[4,3‐__a__]quinoxalines 11–12 were prepared and biologically evaluated for their binding at the benzodiazepine receptor (BZR) in rat cortical membranes. The BZR affinity of 1–10 demonstrates that the presence of a proton