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Patial trisomy 1 due to 1/17 translocation in Ph'-Positive chronic myelocytic leukemia

✍ Scribed by F. Pasquali; D. Francesconi; R. Casalone; G. Ippoliti


Publisher
Springer
Year
1979
Tongue
English
Weight
513 KB
Volume
49
Category
Article
ISSN
0340-6717

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πŸ“œ SIMILAR VOLUMES


Sister chromatid exchange in PH1-positiv
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## Abstract The sister chromatid exchange (SCE) frequency in bone‐marrow cells of 12 untreated patients with chronic myelocytic leukemia (CML) was analysed and compared with the SCE frequency in bone‐marrow cells of nine healthy persons. In normal persons the SCE ranged from 3.64 to 5.15 per cell.

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## Abstract A female patient with chronic myelocytic leukemia (CML) in chronic phase after busulfan and interferon treatment had four different cell lines in her bone marrow. In addition to cells with a normal karyotype there were cells with the Philadelphia chromosome (Ph^1^), cells with trisomy 8