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Pathways of transduction engaged by sphingosine 1-phosphate through G protein-coupled receptors

✍ Scribed by Sandra Siehler; David R Manning


Book ID
117772146
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
110 KB
Volume
1582
Category
Article
ISSN
1388-1981

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## Abstract The lysophospholipid growth factors sphingosine 1‐phosphate (S1P) and lysophosphatidic acid (LPA) are generated by many cells involved in immunity, including macrophages, dendritic cells, mast cells, and platelets, with resultant lymph and plasma concentrations of 0.1–1 ΞΌM. All immune c