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Pathogenic mutations in Parkinson disease

✍ Scribed by Eng-King Tan; Lisa M. Skipper


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
334 KB
Volume
28
Category
Article
ISSN
1059-7794

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R1514Q substitution in Lrrk2 is not a pa
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## Abstract Mutations in __LRRK2__ were first reported as causing Parkinson's disease (PD) in late 2004. Since then, approximately a dozen __LRRK2__ substitutions have been identified that are believed to be pathogenic mutations. The substitution of adenine for guanine at nucleotide 4541 (4541G>A)

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