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Passive and active hepatoma tumor targeting of new N -(2-hydroxypropyl)methacrylamide copolymer conjugates: synthesis, characterization, and evaluation in vitro and in vivo

✍ Scribed by Yuan, Jianchao; Yuan, Bingnian; Guo, Hongyun; Zeng, Xianwu; Wang, Xiaoqi; Liao, Shiqi; Li, Jing; Jia, Zong; Song, Fengying; Wang, Fuzhou


Book ID
121456057
Publisher
Taylor and Francis Group
Year
2013
Tongue
English
Weight
299 KB
Volume
24
Category
Article
ISSN
0920-5063

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## Abstract Trastuzumab (TRZ) is a humanized monoclonal antibody that targets the extracellular domain of the human epidermal growth factor receptor type 2 (Her2). Semitelechelic (ST) poly[__N__‐(2‐hydroxypropyl)methacrylamide]–TRZ conjugates are successfully synthesized and evaluated as a potentia